Acid - Base Medical Diagnosis

診断の酸塩基障害

Short Description:

Acid base disorders are common in critically ill patients and cause high morbidity and mortality (Gunnerson and Kellum, 2003). It is important to appropriately diagnose acid base disorders to appropriately manage them. There are different approaches to diagnose acid base disorders. The most commonly practiced approach is based on Henderson-Hasselbalch method and include Base deficit (BE) and bicarbonate (HCO3) as the metabolic variables. Physicians with novice clinical experience cannot utilize the principles of acid base physiology and pathophysiology for appropriate interpretation of life threatening acid base disorders. For that a computer-based interpretation and even mobile use - based acid base interpretation helps a lot an appropriate management of acid disorders.

This software is following the algorithms based on Henderson-Hasselbalch equation (Po & Senosan, 2001; Constable,2000). It diagnoses also the mixed acid base disorders which cannot picked easily by novice junior physicians. The Henderson-Hasselbalch approach was studied and found to be very effective and valid to diagnose acid base disorders (Radwan, 2013). Junior physicians are the frontline staff who deals frequently with life threatening acid base disorders as in patients having diabetic ketoacidosis, renal failure, shock of distinct categories, and exacerbation of chronic obstructive pulmonary disease(COPD). This software is distinct in two issues; the algorithms start with pH. Other interpretation algorithms start with PaCO2; this messes mixed acid base disorders. The other distinctive character of this software is its ability to diagnose different acid base disorders that occurs in COPD patients. We deduced a new formula to appropriately set the ventilated COPD considering the appropriate PaCO2 level optimal for ventilation and for weaning from mechanical ventilation (Radwan, 1996).